Reactive Oxygen Species‐Responsive Polymeric Prodrug Nanoparticles for Selective and Effective Treatment of Inflammatory Diseases (Adv. Healthcare Mater. 29/2023)

Polymeric Prodrugs In article 2301394 by Zhongyu Li, Weisheng Guo, Weiping Wang and co-workers, a simple reactive oxygen species-responsive prodrug nanosystem is developed to achieve precise cinnamaldehyde release at inflamed sites upon oxidative stress activation, presenting excellent therapeutic efficacy with desired biocompatibility for the treatment of chronic rheumatoid arthritis and acute ulcerative colitis in mice.