Injectable and adhesive hydrogels for dealing with wounds

自愈水凝胶 伤口愈合 伤口敷料 医学 生物粘附 药物输送 外科 纳米技术 材料科学 复合材料 高分子化学
作者
Parisa Ghandforoushan,Nasim Golafshan,Firoz Babu Kadumudi,Miguel Castilho,Alireza Dolatshahi-Pirouz,Gorka Orive
出处
期刊:Expert Opinion on Biological Therapy [Informa]
卷期号:22 (4): 519-533 被引量:12
标识
DOI:10.1080/14712598.2022.2008353
摘要

The development of wound dressing materials that combine healing properties, ability to self-repair the material damages, skin-friendly adhesive nature, and competent mechanical properties have surpassing functional importance in healthcare. Due to their specificity, hydrogels have been recognized as a new gateway in biological materials to treat dysfunctional tissues. The design and creation of injectable hydrogel-based scaffolds have extensively progressed in recent years to improve their therapeutic efficacy and to pave the way for their easy minimally invasive administration. Hence, injectable hydrogel biomaterials have been prepared to eventually translate into minimally invasive therapy and pose a lasting effect on regenerative medicine.This review highlights the recent development of adhesive and injectable hydrogels that have applications in wound healing and wound dressing. Such hydrogel materials are not only expected to improve therapeutic outcomes but also to facilitate the easy surgical process in both wound healing and dressing.Wound healing seems to be an appealing approach for treating countless life-threatening disorders. With the average increase of life expectancy in human societies, an increase in demand for injectable skin replacements and drug delivery carriers for chronic wound healing is expected.
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