腺相关病毒
载体(分子生物学)
重组DNA
病毒学
临床试验
生物
病毒
血清型
重组病毒
医学
生物信息学
基因
遗传学
作者
Richard Snyder,Terence R. Flotte
标识
DOI:10.1016/s0958-1669(02)00369-5
摘要
Recombinant adeno-associated viral (rAAV) vectors are being evaluated in animal models and humans. Pre-clinical data demonstrating vector safety, efficiency and efficacy have been used to initiate human clinical trials. The clinical manufacture of rAAV vectors has supported phase I and phase II trials, showing that adeno-associated virus serotype 2 vectors are safe when administered to humans.
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