Nanocrystal System: A Comprehensive Review of Method of Preparation and their Characterization, Patents and Marketed Products

Nanocrystal drug delivery systems have emerged as a promising method to improve the bioavailability, solubility and therapeutic efficacy of poorly water-soluble drugs. Developed many methods for their creation with top down, bottom down and combination technique. These nanosized particles, usually ranging from 100 to 1000 nm, provide increased surface area, improving dissolution rates and enabling drugs to reach their target more efficiently. This abstract outline the methods for preparing nanocrystals and their characterization, recent marketed formulations and the current trends in patent related to nanocrystal drug delivery systems and their applications. Keywords: Nanocrystal, Method Nanocrystal, Patent, Application