Photoredox (NN)Mn(I) Catalysed Acceptorless Dehydrogenation: Synthesis of Amides, Aldehydes and Ketones

Abstract An acceptorless dehydrogenative methodology for the synthesis of amides, aldehydes and ketones from hemiaminal and alcohols in the presence of manganese(I) based photocatalyst is developed. Several aromatic, aliphatic, heterocyclic aldehydes and primary aryl amines as well as secondary alkyl amines were coupled, providing the corresponding amides. The methodology was also extended for dehydrogenation of various alcohols to get the corresponding carbonyls. The proposed catalytic cycle was supported by various control experiments as well as different analytical techniques such as NMR, IR and ESI‐MS. magnified image