医学
鼻窦炎
前瞻性队列研究
慢性鼻-鼻窦炎
生理盐水
治疗性灌洗
内窥镜检查
外科
随机对照试验
上颌窦
内科学
作者
Ohad Ronen,Tal Marshak,Nechama Uri,Maayan Gruber,O Haberfeld,Dan Paz,Nili Stein,Raanan Cohen‐Kerem
出处
期刊:Journal of Laryngology and Otology
[Cambridge University Press]
日期:2021-09-01
卷期号:136 (3): 229-236
被引量:2
标识
DOI:10.1017/s0022215121002280
摘要
This study aimed to compare the effectiveness of pharmacological therapy with and without direct maxillary sinus saline irrigation for the management of chronic rhinosinusitis without polyps.In this prospective randomised controlled trial, 39 non-operated patients were randomly assigned to be treated with direct maxillary sinus saline irrigation in conjunction with systemic antibiotics and topical sprays (n = 24) or with pharmacological therapy alone (n = 15). Endoscopy, Sino-Nasal Outcome Test and Lund-MacKay computed tomography scores were obtained before, six weeks after and one to two years after treatment.Post-treatment Lund-Mackay computed tomography scores were significantly improved in both cohorts, with no inter-cohort difference identified. Post-treatment nasal endoscopy scores were significantly improved in the study group but were similar to those measured in the control group. The Sino-Nasal Outcome Test-20 results showed improvement in both cohorts, with no difference between treatment arms.Maxillary sinus puncture and irrigation with saline, combined with pharmacological treatment improves endoscopic findings in patients with chronic rhinosinusitis without polyps, but has no beneficial effect on symptoms and imaging findings over conservative treatment alone.
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