Uncontrollable Distant Effects of Botulinum Neurotoxin Injections

Some dentists propose administering botulinum neurotoxin injections to treat orofacial pain. The scientific literature has documented there are dangerous uncontrollable effects of long-distance traveling of botulinum neurotoxin from the injection site. These distant effects are not technique-specific, not predictable, and cannot be controlled by the amount of neurotoxin, nor by the site administered. These uncontrollable distant effects of "off-label" botulinum neurotoxin injections, at the very least, must be thoroughly disclosed to patients.