One hundred and fifty patients(M119, F31; age54+14a)with chronic bronchitis were treated with 2 mL placenta] polypeptides(PP),(placental tissue extract 3 g),im bid for 10 d, then 2 mL qd for 20 d, and then 2 mL qod for 15 d, in addition, conventional therapy with penicillin 800 000 U and streptomycin 0. 5g, im, bid for 45 d, antitussive were given. Seventy similar patients received PP and forty patients received conventional therapy. The results showed that the total response rates of the first group was 84%, the second group 64%, and the third group 55%.The increasing rate of cellular immunity indices of the three groups were 62%,50%, and 40% respectively. It is suggested that PP' can improve the cellular immunity function in patients with chronic bronchitis.