Objective To construct a three-dimensional finite element analysis model of the first mandibular molar with hemisection prosthodontic therapy. Methods After the CT Scanning and image processing, a 3-D geometric model was established by the combination of the AMIRA and Unigraphics NX, the CAD software. The mesh model was then built in ALGOR, the finite element analysis software. Results The three dimensional finite element model was constructed on the computer, which had 47 155 nodes and 41 878 tetrahedrons elements. Conclusion The finite element model constructed has the advantages of intact structure and precise elements,can simulate the natural condition and facilitate the further biomechanical research.