SYNTHESES OF OPTICALLY ACTIVE COMPOUNDS BY YEASTS. I

1. It has been proved that 1-aspartic acid is synthesized from fumaric acid and ammonium chloride by yeast and no aspartic acid is synthesized in the absence of yeast or ammonia. 2. The best yield for the present is 75.599/a of the theoretical. 3. It is presumed that there are 2 mechanisms in reference to the synthesis of l-aspartic acid: a) Fumaric acid+NH3 → l-aspartic acid b) Fumaric acid+NH3 → l-aspartic acid succinic acid+NH3 Fumaric acid → succinic acid+NH3 → l-aspartic acid.