Progress in pharmacological effects of compositions of Astragalus membranaceus

Recent studies have indicated that the main chemical compositions of Astragalus membranaceus include Radix astragali polysaccharide,saponin categories and amino acids.The experimental studies have shown that Astragalus membranaceus can improve immune function;enhance resistance to oxidation;exert anti-radiation and anticancer effects;protect cardiovascular,liver,kidney,lung,and brain cells;improve memory;relax blood vessel smooth muscle;possess the hormone-like,antibacterial and antiviral effects;exert the hypolipidemic and hypoglycemic effects,and reduce complications of diabetes.In clinic,Astragalus membranaceus is widely used in treating circulation,nerve,digestion,respiration,endocrine and blood diseases.Astragalus membranaceus shows no obvious liver and kidney toxicity,but occasionally causes dystocia after misuse in late pregnancy,and mild allergic reactions due to application of the intravenous formulations.This review summarized recent advances in the research of chemical compositions and the pharmacological effects of Astragalus membranaceus.