Inside Cover: Activity Enhancement of G‐Quadruplex/Hemin DNAzyme by Flanking d(CCC) (Chem. Eur. J. 12/2016)

The flanked sequences containing d(CCC) on the core sequence of parallel G-quadruplexes improve the binding affinity of hemin to G-quadruplexes, thereby remarkably enhancing the activity of G-quadruplex/hemin DNAzyme and the hemin degradation by H2O2, as well as increasing the tolerance of DNAzyme to pH change. More information can be found in the Full Paper by D. Shangguan et al. on page 4015 ff.