Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2).

Over the past 15 years it has become clear that drug exporters of the ABC [3][1] family ([1][2]) can both confer MDR to cancer cells and mediate extensive protection of intact organisms against the toxic action of (anticancer) drugs and toxins. The P-gp, MRP1, and MRP2 transporters have all been