医学
倾向得分匹配
腹部外科
肝病学
腹腔镜手术
外科
癌
胃癌
腹腔镜检查
围手术期
回顾性队列研究
普通外科
癌症
胃切除术
内科学
作者
Manabu Yamamoto,Mototsugu Shimokawa,Hiroyuki Kawano,Mitsuhiko Ohta,Daisuke Yoshida,Kazuhito Minami,Masahiko Inamori,Masaru Morita,Yasushi Toh
标识
DOI:10.1007/s00464-018-6325-7
摘要
Laparoscopic surgery is frequently performed, and laparoscopic gastrectomy (LG) is also widely performed for gastric cancer. Elderly population with gastric cancer has increased in East Asia, including in Japan. We examined 1131 patients with gastric cancer who underwent laparoscopic and open standard surgeries (OG). A total of 921 patients of age < 75 years (non-E group) and 210 patients of age ≥ 75 years (E group) underwent surgery for gastric cancer. The mortality, morbidity, and prognosis of LG and OG were compared by propensity score-matched analysis. Mortality and morbidity in the E group were significantly higher than those in the non-E group (p < 0.05). Propensity score-matching revealed that the incidence of postoperative complications of grade ≥ 2 in the OG subgroup was significantly higher than that in the LG subgroup in the E group (p < 0.05). The overall survival rate of the LG subgroup was significantly higher than that of the OG subgroup in both the non-E and E groups (p < 0.05). The depth of tumor invasion, lymph node metastasis, and the number of dissected lymph nodes were dependent factors for survival in the non-E group, whereas the depth of tumor invasion was the only dependent factor for survival in the E group in the multivariate analysis. The survival rate of patients who underwent LG showed significantly good prognosis in both the non-E and E groups, although the E group patients who underwent OG subgroup showed higher severe complication incidences than those who underwent LG subgroup.
科研通智能强力驱动
Strongly Powered by AbleSci AI