金黄色葡萄球菌
气道
鼻息肉
医学
人口
疾病
免疫学
生物
病理
细菌
外科
遗传学
环境卫生
作者
Andrea Renate Teufelberger,Barbara M. Bröker,Dmitri V. Krysko,Claus Bachert,Olga Krysko
标识
DOI:10.1016/j.molmed.2019.05.003
摘要
Staphylococcus aureus persistently colonizes the nostrils of one-third of the population but colonizes the sinus mucosa in up to 90% of patients with nasal polyps, implying a possible role in airway disease. Recent findings give new mechanistic insights into the ability of S. aureus to trigger type 2 inflammatory responses in the upper and lower airways. This novel concept of a S. aureus-driven chronic airway inflammatory disease suggests a new understanding of disease triggers. This article reviews the role of S. aureus in chronic inflammatory airway diseases and discusses possible therapeutic approaches to target S. aureus.
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