[Analysis of the effect of microwave ablation in the treatment of small liver cancer].

Objective: To explore the clinical effect of microwave ablation in the treatment of early small liver cancer (≤3 cm). Methods: 103 cases with small liver cancer (tumor number < 3 and maximum tumor diameter < 3 cm) who underwent microwave ablation from November 2016 to November 2018 were retrospectively collected. The rate of residual lesions, recurrence rate one-year after the operation, and surgical complications were observed and grouped according to tumor size (< 2 cm and≥2 cm group) and tumor numbers (solitary and 2 ~ 3 lesion groups). The therapeutic effects of each group were compared and analyzed. Results: The tumor residual rate and one-year recurrence rate of small liver cancer after microwave ablation were 11.7% and 35.0%, respectively. The post-ablation syndrome incidence rate was 52.4%, with no serious adverse events. Compared with tumors < 2 cm, patients with≥2 cm had a higher postoperative residual rate (χ(2) = 7.651, P = 0.006), and the one-year recurrence rate of more solitary nodular tumors was lower (χ(2) = 10.125, P = 0.001). Conclusion: Microwave ablation is a safe and effective treatment for early small liver cancer, and it is more effective for small solitary nodules (< 2 cm).目的： 探讨微波消融治疗早期小肝癌（≤3 cm）的临床效果。 方法： 回顾性搜集2016年11月至2018年11月行微波消融治疗的103例小肝癌（肿瘤数目不超过3个，肿瘤最大直径不超过3 cm）患者，观察手术后病灶残留率、术后1年复发率和手术并发症。按肿瘤大小分为< 2 cm和≥2 cm组，按肿瘤数目分为单个和2~3个病灶组，对比分析各组治疗效果。 结果： 小肝癌微波消融治疗术后肿瘤残留率、1年复发率分别为11.7%、35.0%，消融后综合征发生率为52.4%，无严重不良事件发生。对比< 2 cm肿瘤，≥2 cm患者术后残留率更高（χ(2) = 7.651，P = 0.006），单个肿瘤的1年复发率较多结节肿瘤更低（χ(2) = 10.125，P = 0.001）。 结论： 微波消融是早期小肝癌安全有效的治疗方法，对单发小结节（< 2 cm）肿瘤效果更好。.