Template-Directed Synthesis of Oligonucleotide. Condensation of Nucleotide in the Presence of Polystyrene-Supported Neutral Oligonucleotide Derivative

Abstract A template-directed synthesis of oligonucleotide in the presence of polystyrene-supported neutral oligonucleotide derivative was studied. The oligonucleotide which has the sequence of the complementary base with the template, the neutral oligonucleotide derivative, yielded with a considerable amount, when the template with degree of oligomerization of 4 was used.