Effect of Chimonin on activity of CR_1 and LPO level of ageing erythrocytes

Experiments were undertaken in Chimonin on the activity of CR1 and the level of liPid Peroxide in vitro. RBC-C3bRR、RBC-ICR and RBC-CaR in the group of 50μg and 100μg are higher than those in the group of 5μg、10μg (P0.05)after the ageing erythrocytes preincubated with chimonin; simultaneously, the ageing erythrocytes to investigate the effects of content of LPO of ageing erythrocytes decreased with dose dependent effect(P0.01).It is suggested that lipid peroxidation may participate in the activity of CR1 of ageing erythrocytes.