Clinical characteristics of 14 cases of Chlamydia psittaci pneumonia.

降钙素原 鹦鹉热衣原体 内科学 肌酐 医学 肺炎 胃肠病学 白细胞 乳酸脱氢酶 血尿素氮 C反应蛋白 败血症 免疫学 衣原体 生物 炎症 生物化学
作者
Binbin Cheng,Jun Wang,Lin Lin,Dexiang Yang,Xiaofeng Liu,Hao Wu
出处
期刊:PubMed 卷期号:46 (4): 416-423 被引量:1
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Among 14 patients with C. psittaci pneumonia, there were 9 critical and 5 non-critical cases. Ten patients improved clinically and were discharged to home; however, four patients died. Seven patients had a history of contact with birds or poultry. All 14 patients had a high fever as the presenting symptom, but most had a normal white blood cell count. Most of the patients had a significant increase in high-sensitivity C-reactive protein and procalcitonin levels. The lymphocyte count in the critical group was considerably lower than in the non-critical group. Patients in the critical group were more advanced in age than in the non-critical group. In addition, serum urea nitrogen, creatinine, procalcitonin, and lactate dehydrogenase levels were significantly higher in the critical group than in the non-critical group (P<0.05). The 4 patients who died had significantly increased procalcitonin levels compared to the 10 patients who survived (P<0.05). In summary, a high fever is usually the presenting complaint of patients with C. psittaci pneumonia. Such patients often progress to severe disease; however, early diagnostic confirmation by mNGS and appropriate treatment dramatically improve the prognosis. Age, lymphocyte count, procalcitonin, blood urea nitrogen, creatinine, and lactate dehydrogenase levels were shown to predict disease severity.

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