Progranulin (PGRN) Facilitates Anti‐Inflammation and Pulpitis Repair In Vivo and In Vitro Through TNFR2/14‐3‐3ε Signalling Complex

These findings suggest that PGRN plays a crucial role in anti-inflammation, immunomodulation and reparative dentinogenesis in rat pulpitis via the TNFR2/14-3-3ε-NF-κB pathway, highlighting its potential as a strategy for vital pulp therapy.