无机化学
化学
多样性(控制论)
试剂
有机合成
溶剂
催化作用
组合化学
二甲基甲酰胺
有机化学
环境化学
计算机科学
人工智能
作者
Qiang Yang,Min Sheng,Yong‐Liang Huang
标识
DOI:10.1021/acs.oprd.0c00330
摘要
N,N-Dimethylformamide (DMF) is frequently used as a solvent because of its unique physical properties that allow it to solubilize both organic and inorganic substances. It has also found broad applications as a catalyst for a variety of chemical transformations and as a donor for many functional groups in synthetic organic chemistry. However, DMF is incompatible with a wide variety of substances and has resulted in many incidents over the years. Analysis of literature information indicates that those incompatible substances can be categorized as acids, bases, halogenated reagents, oxidants, and reductants. This comprehensive review of the potential hazards of using DMF in chemical reactions will serve as an educational resource to promote awareness of such safety hazards in the broader chemistry community and encourage scientists to develop appropriate control strategies to mitigate the potential safety risks associated with the use of DMF in chemical reactions.
科研通智能强力驱动
Strongly Powered by AbleSci AI