New Evaluation Criteria for Response and Toxicity in Lung Cancer Treatment

Response Evaluation Criteria in Solid Tumors (RECIST) and the National Cancer Institute — Common Toxicity Criteria (NCI-CTC) Version 2.0 were prepared for the purpose of standardizing the evaluation criteria for response and toxicity of cancer treatment. Objective response evaluation in RECIST has been simplified from the method using bidimensional measurement (product of 2 diam- eters) in WHO Standards to the summation of unidimensional measurement (largest diameter). NCI-CTC Version 2.0 includes toxicities and categories that have been increased from 49 toxicities in 18 categories in the previous version to 279 toxicities in 24 categories. It also provides more appropriate toxicity evaluation by grading of associated toxicities.