Photoredox Catalysis Mediated Application of Methyl Fluorosulfonyldifluoroacetate as the CF2CO2R Radical Source

A new application of trifluoromethylating reagent, methyl fluorosulfonyldifluoroacetate (FO 2 SCF 2 CO 2 Me, Chen’s reagent), as the carbomethoxydifluoromethylating reagent under visible light photoredox conditions is reported. The visible-light-induced reaction of FO 2 SCF 2 CO 2 Me with unactivated alkenes, styrenes, or heteroarenes affords a variety of carbomethoxydifluoromethylated products.