Iatrogenic Cerebral Amyloid Angiopathy After Cardiac Surgery

These 2 cases add to the growing evidence regarding Aβ transmissibility in humans and remove the confounding factor of neurosurgery. Iatrogenic CAA diagnosis should be considered after exclusion of genetic causes in patients with early-onset clinical and neuroimaging features of CAA. Patient should have evidence of Aβ accumulation in the CNS and a suggestive medical history. Treatments at risk should not be limited to neurosurgery and should namely include cardiovascular procedures with CNS tissues such as cadaveric DM or exposure to cadaveric human growth hormone.