骨肉瘤
癌症研究
医学
免疫疗法
翻译(生物学)
T细胞
病理
癌症
肿瘤细胞
癌细胞
细胞毒性T细胞
T淋巴细胞
细胞培养
免疫学
免疫系统
体外
化疗
作者
Carla O'Reilly,Shraddha Tuladhar,Phuong Nguyen,Heather Sheppard,Selene C. Koo,Peter Chockley,Haley Houke,Teresa Santiago,Liqing Tian,Julie Jeschke,Alex N. Beckett,Ashley Chabot,Jason T. Yustein,Giedre Krenciute,Lindsay J. Talbot,Stephen Gottschalk,Christopher DeRenzo
标识
DOI:10.1158/1078-0432.ccr-24-2335
摘要
LRRC15-CAR T cells exert anti-osteosarcoma activity while maintaining a positive safety profile. These promising findings support clinical translation of LRRC15-CAR T cells for patients with osteosarcoma and potentially other LRRC15-positive solid tumors.
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