Erector Spinae Block versus Serratus Plane Block for postoperative analgesia in breast and thoracic surgery: A meta-analysis of Randomized controlled Trial

Review question / Objective: Patients of 18 years or older undergoing breast and thoracic surgery (P); patients received erector spinae plane block (I);patients received serratus plane block (C); analgesic efficacy measured as postoperative pain, use of intra and postoperative opioids, postoperative sideeffects, such as nausea and vomiting, and respiratory complications, dizziness, time for chest tube removal and LOS (O); Randomized controlled Trials (S).Condition being studied: Ultrasound-guided erector spinae plane block (ESPB) is a newly defined regional anesthesia technique, first introduced by Forero et al. in 2016, has rapidly gained popularity in different types of surgeries, such as breast, thoracic, abdominal, and lumbar surgery.It is typically performed via deposition of local anesthetic into the fascial plane, beneath the erector spinae muscle at the tip of the transverse process of the vertebra that can blocking the branches of the thoracic and abdominal spinal nerves.The benefits of ESPB have been well established, including reduced postoperative pain scores, decreased opioid requirements, and lower risks of postoperative nausea and vomiting (POVN).Serratus anterior plane block (SAPB) is a type of interfacial plane block that was defined by Blanco in 2013.SAPB blocks the lateral branches of the intercostal nerves (T2-T9) so that it can provide analgesia in the chest wall.It has been reported that SAPB may be used to provide postoperative analgesia after thoracoscopic, breast surgery.INPLASY registration number: This protocol was registered with the International Platform of Registered Systematic Review and Meta-Analysis Protocols (INPLASY) on 19 December 2021 and was last updated on 19 December 2021 (registration number INPLASY2021120085).