医学
杜瓦卢马布
癌症研究
肿瘤科
细胞因子
内科学
乳腺癌
表型
癌症
免疫学
趋化性
乳腺
CA15-3号
人体乳房
作者
Kim R.M. Blenman,Michal Marczyk,Thomas Karn,Tao Qing,Xiaotong Li,Vignesh Gunasekharan,Vesal Yaghoobi,Yalai Bai,Eiman Y. Ibrahim,Tristen Park,Andrea Silber,Denise M. Wolf,Emily Reisenbichler,Carsten Denkert,Bruno V. Sinn,Mariya Rozenblit,Julia Foldi,David L. Rimm,Sibylle Loibl,Lajos Pusztai
标识
DOI:10.1158/1078-0432.ccr-21-3215
摘要
The TGFβ pathway is associated with immune-poor phenotype and RD in bTNBC. Among immune-rich bTNBC RD, macrophage/neutrophil chemoattractants dominate the cytokine milieu, and IFNγ and activated B cells and T cells dominate immune-rich cancers with pCR.
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