医学
肾切除术
吉西他滨
卵巢肿瘤
转移
颗粒细胞
卵巢
卡铂
化疗
透明细胞腺癌
内科学
清除单元格
泌尿科
肾细胞癌
肿瘤科
肾
卵巢癌
癌症
顺铂
作者
Kyo Togashi,T. Yoneyama,Mihoko Sutoh Yoneyama,Hayato Yamamoto,Shingo Hatakeyama,Takahiro Yoneyama,Yasuhiro Hashimoto,Masayuki Futagami,Chikara Οhyama
摘要
We would like to present a rare case of metastatic renal tumor.A 60-year-old woman presented to our department with a left renal tumor. She underwent a total hysterectomy and right adnexal resection for a stage IA ovarian granulosa cell tumor approximately 15 years ago, followed by left adnexal resection and postoperative chemotherapy with gemcitabine and paclitaxel 6 years ago. She received six courses of gemcitabine and carboplatin to treat a stage IC clear cell adenocarcinoma of the ovary.The patient was diagnosed with the left renal tumor and underwent a laparoscopic left nephrectomy. Immunostaining was positive for α-inhibin and SF-1 and showed FOXL2 402C→G (C134W) mutation. Finally, the patient was diagnosed with renal metastasis of a granulosa cell tumor.To our knowledge, this is a very rare case of renal metastasis of a granulosa cell tumor with the FOXL2 mutation in an adult.
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