维生素D与神经学
麦角钙化醇
医学
骨化三醇
糖尿病性视网膜病变
维生素D缺乏
胆钙化醇
糖尿病
维生素缺乏症
内科学
内分泌学
维生素
皮肤病科
作者
Antonela Gverović Antunica,Ljubo Znaor,Mira Ivanković,Velibor Puzović,Irena Marković,Snježana Kaštelan
标识
DOI:10.3390/ijms241512014
摘要
Diabetic retinopathy (DR) is the most common eye disease complication of diabetes, and hypovitaminosis D is mentioned as one of the risk factors. Vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol) are the best-known forms of vitamin D. Calcitriol (1,25-dihydroxycholecalciferol) is the active form of vitamin D, with the sun being one of its main sources. Vitamin D is synthesized in the skin by exposure to sunlight without protective factors, but care must be taken to avoid the development of sunburn. It not only plays an important role in maintaining healthy bones and immune system but has also been highlighted in numerous studies to have an influence on various diseases, including diabetic retinopathy. A large number of people suffer from vitamin D hypovitaminosis worldwide, and diagnosis is made by measuring the concentration of 25-hydroxyvitamin D (25(OH)D) in serum. Its deficiency can cause numerous diseases and, as such, supplementation is necessary. Clinical studies have proven the effectiveness of vitamin D supplementation in the treatment of diabetic retinopathy, but with a doctor’s recommendation and supervision due to possible negative side effects.
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