Biopolymer based Fibrous Aggregate Materials for Diagnosis and Treatment: Design, Manufacturing, and Applications

Biopolymer-based fibrous aggregate materials (BFAMs) have gained increasing attention in biomedicine due to their excellent biocompatibility, processability, biodegradability, and multifunctionality. Especially, the medical applications of BFAMs demand advanced structure, performance, and function, which conventional trial-and-error methods struggle to provide. This necessitates the rational selection of materials and manufacturing methods to design BFAMs with various intended functions and structures. This review summarizes the current progress in raw material selection, structural and functional design, processing technology, and application of BFAMs. Additionally, the challenges encountered during the development of BFAMs are discussed, along with perspectives for future research offered.