Short Sleep Duration Increases the Risk of Chronic Kidney Disease in Shift Workers

Objective: To investigate the association of sleep duration and shift work with development of chronic kidney disease (CKD) in Japanese workers. Methods: A total of 3600 participants without CKD were observed for an average of 4.4 years. The Cox proportional-hazards regression model was used to estimate hazard ratios and 95% confidence intervals of the risk of CKD associated with sleep duration and shift work. Results: Sleep duration and shift work showed no significant association with the risk of CKD. Nevertheless, when the results were stratified by shift work status, short sleep duration was associated with a significantly higher risk of CKD among shift workers (hazard ratio = 3.60; 95% confidence interval: 1.52 to 10.68). Conclusions: Short sleep duration was a risk factor for early CKD but only among shift workers.