Biomarkers for the diagnosis of Kawasaki disease

Kawasaki disease (KD) is an acute, self-limiting systemic vascular syndrome that mainly occurs in infants and children under the age of five years, and is the leading cause of acquired heart disease in children.Kawasaki disease can lead to coronary dilatation, coronary aneurysm, which can cause myocardial infarction or death, seriously harm the health of infants and children, and thus early diagnosis is critically important.Till now the diagnosis is based mainly on the clinical symptoms for the lack of diagnostic laboratory tests.In recent years, many studies have been carried out to explore the potential biomarkers with high sensitivity and specificity in the early diagnosis of KD.The article reviews the progress of the related studies. Key words: Kawasaki disease; Biomarker; Diagnosis