化学
马兜铃酸
三聚氰胺
固相萃取
吸附
解吸
检出限
萃取(化学)
傅里叶变换红外光谱
红外光谱学
色谱法
核化学
化学工程
有机化学
遗传学
生物
工程类
作者
Hua Shu,Guoning Chen,Lu Wang,Xia Cui,Zhimin Luo,Wanghui Jing,Chun Chang,Aiguo Zeng,Jia Zhang,Qiang Fu
标识
DOI:10.1016/j.chroma.2021.462155
摘要
Aristolochic acid Ⅰ is a nephrotoxic compound and exist in some traditional Chinese medicines at trace level. Up to now, specific enrichment of aristolochic acid Ⅰ remains important procedure and key problem in its analysis. In this study, melamine was proposed as the recognition unit and grafted on the surface of metal-organic framework to fabricate a specific material for aristolochic acid Ⅰ. This material was prepared by using a two-step strategy and the preparation process was optimized. The physical and chemical properties were investigated using scanning electron microscopy, Fourier-transfer infrared spectroscopy, X-ray diffraction and nitrogen adsorption-desorption techniques. Adsorption properties were evaluated by binding experiments. The melamine modified material exhibited a uniform morphology, high specific surface area (460.20 m2 g−1), high adsorption capacity (25.57 mg g−1), fast mass transfer rate and excellent selectivity. Further, a specific and sensitive method was established by using this material as adsorbent of mini-solid phase extraction. The limit of detection was as low as 0.02 μg mL−1. Therefore, melamine modified metal-organic framework is an ideal adsorbent for the recognition and enrichment of aristolochic acid Ⅰ.
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