纳米纤维
自愈水凝胶
肽
药物输送
纳米技术
化学
控制释放
高分子科学
计算机科学
材料科学
高分子化学
生物化学
作者
Ying Zhao,Tianwei Tan,Hidenori Yokoi,Masayoshi Tanaka,Takatoshi Kinoshita
摘要
In this work, we report a new peptide RATEA16 nanofiber hydrogel as a drug delivery system for protein, and the protein-nanofiber assemblies are formed based on hydrophobic and electrostatic interactions. The loading/release process is reversible by changing media pH, and the protein released from the hydrogel returned its native structure. Therefore, it offers new prospects for preparing peptide hydrogel for special biomedical applications. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.] This article contains Supplementary Material available via the Internet at http://www.interscience.wiley.com/jpages/0887-624X/suppmat . Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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