Quantitative assessment of perfusion in coronary microcirculation by transvenous myocardial contrast echocardiography

Objective To evaluate quantitatively perfusion in coronary microcirculation by transvenous myocardial contrast.echocardiography(MCE).Methods Transvenous MCE was performed before and after LAD stenosis in 12 dogs.Results Peak intensity and area under curve(AUC)in time-intensity curves were significantly decreased after LAD stenois,peak intensity and AUC were strongly related with CBF flow(peakintensity:r=0.9405～0.09666,P=0.0005～0.0001;AUC:r=0.8239～0.9761,P=0.0103～ 0.0056).Conclusion Transvenous MCE could quantitatively assess the perfusion in coronary microcirculation. Key words: Echocardiography; Coronary vessels; Microcirculation; Contrast media