Determination of Camphor and Borneol in Oral Tablets of Chrysanthemum morifolium Essential Oil

Objective:To establish an GC method for the determination of camphor and borneol in oral tablets of Chrysanthemum morifolium essential oil in β-cyclodextrin inclusion.Methods:The camphor and borneol in inclusion tablets were extracted by refluxed.The contents of two effective components were analyzed by gas chromatography with CBP20-M25-025 capillary column.N-octanol was used as internal standard substance for camphor and borneol.Results:A good separation was obtained.The standard curves for camphor and borneol were linear over the range of 14.00～224.0μg·mL-1 and 19.69～315.0μg·mL-1,respectively.The average recovery for camphor and borneol was higher than 94.2%.The precisions for them were both less than 0.77%.Conclusion:The method is accurate and sensitive for the determination of camphor and borneol in inclusion tablets of Chrysanthemum morifolium essential oil with good quality controlling of oral tablet product,providing scientific evidence for the development of Chrysanthemum morifolium and reasonable clinical application of essential oil.