Panax notoginsengsaponins(PNS)is the main active ingredient of traditional Chinese medicine of Panax notoginseng,which has a wide range of biological activity in the central nervous system,cardiovascular system and blood system,as well as anti-inflammatory,anti-fibrotic,anti-aging and anti-tumor.PNS has become a hot spot in the field of Chinese medicine and pharmacology.In recent years,biological activity of PNS is further studied and widely applicated.In this paper,the studies and uses of PNS are reviewed,and prospects are discussed.