This work investigated the application of ceramic membrane microfiltration of the slurry system of TiO2-PAM.Three main kinds of membrane resistance were found in the microfiltration process,i.e.intrinsic membrane resistance(Rm),filtration cake resistance(Rc) and pore blockage resistance(Ri).The effects of back-flushing and turbulence promoter introduction,and efficient cleaning methods for the fouled membrane were also investigated in detail.For the microfiltration of TiO2 slurry,Rm was the main membrane resistance and the secondary was Rc;turbulence promoter and back-flushing could efficiently enhance the process.Physical cleaning and chemical cleaning with 0.1 mol/L HNO3could effectively recover the permeance of membrane.For the microfiltration of PAM solution and PAM-TiO2 slurry system,pore blockage was the main membrane resistance;turbulence promoter could reduce the pore blockage.Chemical cleaning with c(HNO3)=0.1 mol/L+ c(NaOH) =0.1 mol/L +w(H2O2) =1% show the best results,recovering 96.5% permeance of membrane.