Objective To compare the effect of time choice on Slow-flow No-reflow(SNR) phenomena in patients with acute myocardial infarction(AMI) who underwent percutaneous coronary intervension(PCI).Methods 272 patients receiving PCI were enrolled.According to TIMI flow,the patients were divided into 2 study populations,who were divided into 3 groups according to immediate PCI or elective PCI,respectively.Results Patients receiving PCI from 24h to one week had more incidence of SNR according to 2 study populations(22/28 vs 8/60,22/28 vs 16/48 P0.05)(14/31 vs 6/62,14/31 vs 4/43,P0.05).Furthermore,patients of immediate PCI had less SNR incidence than those receiving PCI from one week to one month according to TIMI grade 2(8/60 vs 16/48,P0.05).Achievement of TIMI flow grade 3 according to TIMI grade 3 had no significant difference in patients receiving PCI from 24h to one week and those immediate PCI(6/62 vs 4/43,P0.05).Patients receiving PCI from 24h to one week had higher mortality of SNR in TIMI grade 2 group,compared with TIMI grade 3 group(22/28 vs 14/31,P0.05).Conclusion Patients with AMI who underwent immediate PCI had less SNR incidence than those of patients who received elective PCI.