The results of the second-line drug susceptibility testing in 41 MDR-TB patients

Objective To understand the condition of the second-line drug susceptibility testing in multidrug-resistant tuberculosis(MDR-TB) patients in Binzhou city from 2009 to 2011 and to provide evidences for making the treatment regimens.Methods The absolute concentration method was used in drug susceptibility testing with 4 kind of second-line anti-TB drug in 41 confirmed MDR-TB cases.Results In 41 MDR-TB cases,14.6% was resistant to KM,9.8% was resistant to AMK,7.3% was resistant to LFX and 4.9% was resistant to CPM.65.9% of the MDR-TB strains were sensitive to the 4 kind of second-line anti-TB drugs,and XDR-TB accounted for 2.4%.Conclusions The second-line anti-TB drug susceptibility testing will help us to make the standard individual treatment regimens for the MDR-TB patients.