维尔达格利普汀
化学
产量（工程）
胺化
乙酰化
组合化学
氯化物
有机化学
生物化学
生物技术
催化作用
冶金
胰岛素
材料科学
基因
生物
二甲双胍
作者
Yu Deng,An Min Wang,Zhu Tao,Yingjie Chen,Xinmei Pan,Xiangnan Hu
标识
DOI：10.2174/1570178611666140922121805
摘要
A mild and economical method to prepare vildagliptin had been reported with a good yield. In this paper, vildagliptin was synthesized from L-proline and 3-amino-1-adamantanol through chloride acetylation, amination, dehydration and substitution. The total yield of the target compound was 59%. Keywords: Economical, synthesize, vildagliptin.
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