嵌合抗原受体
T细胞
CD8型
表型
瓶颈
计算机科学
细胞
生物
细胞生物学
化学
抗原
免疫学
免疫系统
遗传学
嵌入式系统
基因
作者
Vladislav Markelov,Konstantin V. Arabuli,Ivan Gaponenko,Vladislav S. Sergeev,Alena I. Shakirova,Kirill V. Lepik,Alexander Kulagin,Mikhail V. Zyuzin
出处
期刊:Lab on a Chip
[Royal Society of Chemistry]
日期:2025-01-01
卷期号:25 (12): 3005-3015
被引量:1
摘要
A microfluidic device was developed for ultrafast CAR-T cell production, enabling manufacturing within 24 hours. T-cell quality was enhanced, with naive-like phenotypes preserved and higher transduction rates achieved compared to standard methods.
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