光动力疗法
冷冻疗法
医学
无症状的
增生
人乳头瘤病毒
烧蚀
口腔粘膜
皮肤病科
病理
外科
内科学
化学
有机化学
作者
Xin Tian,Zhenglei Li,Hongxia Dan,Xin Zeng,Qianming Chen,Jiongke Wang
标识
DOI:10.1016/j.pdpdt.2023.103757
摘要
Focal epithelial hyperplasia (FEH) is an uncommon benign disorder affecting the oral mucosa. It is primarily associated with human papillomavirus (HPV) infection and presents as multiple white or pink soft papules or nodules. Typically, FEH is asymptomatic. Conventional treatment approaches for FEH include topical medication, surgical excision, CO2 laser ablation, cryotherapy, etc., but their efficacy varies. Photodynamic therapy (PDT) is a non-invasive and selective photochemotherapy method widely utilized in clinical practice. By employing specific light wavelengths to activate photosensitizers and induce the generation of reactive oxygen, PDT exerts cytotoxic effects. However, the application of PDT in treating FEH has not been previously documented. In this study, we present a case demonstrating the complete remission of FEH lesions using PDT, with no recurrence observed over a period of 9 months. This compelling outcome suggests that PDT may be a preferred treatment modality for FEH.
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