布拉格峰
质子疗法
剂量学
束流扫描
监视器单元
闪光灯(摄影)
质子
梁(结构)
核医学
光学
材料科学
医学
物理
核物理学
作者
Patricia van Marlen,Steven van de Water,Ben J. Slotman,Max Dahele,Wilko F.A.R. Verbakel
摘要
High-energy transmission beams (TBs) are currently the main delivery method for proton pencil beam scanning ultrahigh dose-rate (UHDR) FLASH radiotherapy. TBs place the Bragg-peaks behind the target, outside the patient, making delivery practical and achievement of high dose-rates more likely. However, they lead to higher integral dose compared to conventional intensity-modulated proton therapy (IMPT), in which Bragg-peaks are placed within the tumor. It is hypothesized that, when energy changes are not required and high beam currents are possible, Bragg-peak-based beams can not only achieve more conformal dose distributions than TBs, but also have more FLASH-potential.
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