Epigenetic Contributors to PTSD: a Comprehensive Review.

Epigenetic modifications, particularly DNA methylation, play a significant role in PTSD pathophysiology. While specific gene methylation changes are associated with PTSD, the link between PTSD and epigenetic aging remains unclear. Variability across studies suggests that trauma type, duration, and genetic factors may influence these epigenetic processes. Further research is essential to fully understand these relationships.