作者
Karine E. Manera,David W. Johnson,Jonathan C. Craig,Jenny I. Shen,Talia Gutman,Yeoungjee Cho,Angela Yee-Moon Wang,Edwina A. Brown,Gillian Brunier,Jie Dong,Tony Dunning,Rajnish Mehrotra,Saraladevi Naicker,Roberto Pecoits-Filho,Jeffrey Perl,Martin Wilkie,Allison Tong,Adeera Levin,Adrian Liew,Alfonso Cueto Manzano,Ali K. Abu Alfa,Alicia M. Neu,Amanda Baumgart,Amelie Bernier-Jean,Amy Kelly,Ana Elizabeth Figueiredo,Andrea Matus,Andrea K. Viecelli,Angela Ju,Anjali B. Saxena,Ankit Sharma,Annie-Claire Nadeau-Fredette,Armando Teixeira-Pinto,Asher A. Mendelson,Ayano Kelly,Bak Leong Goh,Bénédicte Sautenet,Braden J. Manns,Brenda R. Hemmelgarn,Bruce G. Robinson,Camilla S. Hanson,Catherine Cheung,Chandana Guha,Charlotte Logeman,Cheuk-Chun Szeto,Claudia Rutherford,Daniel Schwartz,Daniel Sumpton,David W. Johnson,David C. Wheeler,Edwina A. Brown,Emma O'Lone,Eric Au,Eric Goffin,Fred Finkelstein,Georgi Abraham,Greg Germino,Helen Hurst,Hideki Kawanishi,Htay Htay,Hui-Kim Yap,Isaac Teitelbaum,Jenny Chen,Jenny Shen,Joanna Neumann,Joanne M. Bargman,Johann Morelle,Jonathan C. Craig,Kajiru Kilonzo,Karen Yeates,Karine Manera,Karolis Azukaitis,Kim Linh Van,Louese Dunn,Mahesh Krishnan,Mark Lambie,Martin Howell,Martin Schreiber,Matthew J. Oliver,Mauricio Rafael Sanabria,Melissa Nataatmadja,Monika Lichodziejewska-Niemierko,Nancy Verdin,Neelam Mann,Neil Boudville,Nicole Evangelidis,Nicole Scholes-Robertson,Peter G. Blake,Peter Nourse,Peter Tugwell,Philip Kam-Tao Li,Richard McGee,Robert R. Quinn,Sally Crowe,Samaya Anumudu,Sarah Bernays,Sarala Naicker,Scott Wilson,Sharon J. Nessim,Sharon Teo
摘要
Outcomes reported in randomized controlled trials in peritoneal dialysis (PD) are diverse, are measured inconsistently, and may not be important to patients, families, and clinicians. The Standardized Outcomes in Nephrology-Peritoneal Dialysis (SONG-PD) initiative aims to establish a core outcome set for trials in PD based on the shared priorities of all stakeholders. We convened an international SONG-PD stakeholder consensus workshop in May 2018 in Vancouver, Canada. Nineteen patients/caregivers and 51 health professionals attended. Participants discussed core outcome domains and implementation in trials in PD. Four themes relating to the formation of core outcome domains were identified: life participation as a main goal of PD, impact of fatigue, empowerment for preparation and planning, and separation of contributing factors from core factors. Considerations for implementation were identified: standardizing patient-reported outcomes, requiring a validated and feasible measure, simplicity of binary outcomes, responsiveness to interventions, and using positive terminology. All stakeholders supported inclusion of PD-related infection, cardiovascular disease, mortality, technique survival, and life participation as the core outcome domains for PD.