Secondary Metabolites of Aspergillus fumigatus var. fumigatus

AIM: To study the secondary metabolites of the commensal microorganism (Aspergillus fumigatus var. fumigatus) of Cephalotaxus mannii. METHOD: Chemical constituents were isolated by column chromatography and structures were elucidated based on spectral analysis. RESULT: Two compounds were purified from the fermented extracts and identified to be trypacidin (1) and 1,2-seco-trypacidin (2), respectively. CONCLUSION: Compound 2 is a new compound, and the 13C NMR assignments for the C-4 and C-7a of trypacidin were revised based on HMQC and HMBC experiments.