LIPID SYNTHESIS (14C-ACETATE INCORPORATION) IN THE ISOLATED HUMAN SEBACEOUS GLAND, THE APPENDAGE-FREED EPIDERMIS, THE SEBOCYST (STEATOCYSTOMA) AND THE WEN (KERATINOUS CYST OF SKIN)

Summary.— The patterns of incorporation in vitro of 14C‐acetate into the lipid classes of the isolated human sebaceous gland and overlying appendage‐freed epidermis have been compared with those obtained from the sebocyst (steatocystoma) and the wen (keratinous cyst of skin). The characteristic pattern of incorporation obtained from the wen resembled that of appendage‐freed epidermis, thus confirming previous histological and biochemical reports that these cysts are not of sebaceous origin. Two patterns of incorporation were obtained from the sebocysts; one closely resembled that of the isolated sebaceous gland, and one of the appendage‐freed epidermis. These biochemical findings can be directly related to previous histological studies of the sebocyst.