A New Method for α-Selective Glycosylation Using a Donor, Glycosyl Methyldiphenylphosphonium Iodide, without Any Assistance of Acid Promoters

Abstract A mild and highly α-selective glycosylation of several glycosyl acceptors was performed with an in situ formed glycosyl donor, benzyl-protected glycosyl methyldiphenylphosphonium iodide, to afford the corresponding α-disaccharides in high yields in CH2Cl2 at room temperature without any assistance of acid promoters.