脂质体
甘露糖受体
跨细胞
内吞作用
药物输送
体内
肽
肿瘤微环境
化学
癌症研究
巨噬细胞
细胞生物学
体外
受体
生物化学
免疫系统
免疫学
医学
生物
有机化学
生物技术
作者
Yixuan Tang,Zhongjie Tang,Pingrong Li,Kaicheng Tang,Zhongyi Ma,Yantong Wang,Xiaoyou Wang,Chong Li
出处
期刊:ACS Nano
[American Chemical Society]
日期:2021-11-09
卷期号:15 (11): 18100-18112
被引量:54
标识
DOI:10.1021/acsnano.1c06707
摘要
studies demonstrated that doxorubicin-loaded liposomes efficiently eliminated M2 TAMs but did not affect M1 TAMs, enhancing the potency of the antitumor therapy. Collectively, our results demonstrate the potential of combining active escape and active targeting for precisely delivering a drug of interest to M2 macrophages and suggest its application in anticancer therapy.
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